How Medications Affect Heart Rhythms
April 8, 2025

Arrhythmias, or irregular heartbeats, can be influenced by a variety of factors, including lifestyle, underlying health conditions, and medications. While some drugs help regulate heart rhythm, others can unintentionally trigger or worsen arrhythmias. Understanding which medications impact heart function and how to manage potential side effects is crucial for maintaining optimal cardiovascular health.
Medications That Can Influence Heart Rhythms
Arrhythmias, or irregular heartbeats, can be influenced by a variety of factors, including lifestyle, underlying health conditions, and medications. While some drugs help regulate heart rhythm, others can unintentionally trigger or worsen arrhythmias. Understanding which medications impact heart function and how to manage potential side effects is crucial for maintaining optimal cardiovascular health.
Antiarrhythmic Drugs
Some medications designed to treat arrhythmias can also cause them in certain cases. These drugs work by modifying electrical impulses in the heart, but they must be carefully managed. Examples: Amiodarone, Flecainide, Sotalol Potential Effects: While they help regulate heartbeat, they can sometimes cause bradycardia (slow heart rate) or proarrhythmic effects (worsening irregular rhythms).
Beta-Blockers and Calcium Channel Blockers
These medications are commonly used to manage high blood pressure and heart conditions, including atrial fibrillation. Examples: Metoprolol, Propranolol, Verapamil, Diltiazem Potential Effects: They slow heart rate and reduce the workload on the heart but may cause excessively slow heartbeats in some individuals.
Psychiatric Medications
Certain antidepressants and antipsychotics can interfere with heart rhythms by prolonging the QT interval, which increases the risk of dangerous arrhythmias. Examples: Citalopram, Fluoxetine, Haloperidol, Quetiapine Potential Effects: QT prolongation can lead to life-threatening conditions like Torsades de Pointes.