In short, SNPs are what make each one of us who we are. Less than 1% of the total DNA among the human population is dissimilar. However, that 1% makes a big difference, and those differences are found within SNPs. SNPs are the most common type of genetic variation and are an exchange in the DNA code of one nucleotide for another. There are over 20 million known SNPs that have been validated, and they’ve been used as the basis for genetic studies. The study of SNPs has helped to identify predictive markers that point to genetic predispositions for certain diseases and health conditions. And we now know that the more SNPs are analyzed, the more accurate results are.
Which SNPs Does CardioDNATM Analyze?
Cardiogram offers our own cardiac DNA testing, CardioDNATM. These genetic tests analyze four SNPs that have been well researched as identifiers for cardiac disease risk, and together provide a picture of your overall cardiac health. These specific SNPs are KIF6, MYH15, PALLD, and SNX19 and analyzing them allows us to tell you your risk of the following cardiac disease:
- Coronary artery disease
- Myocardial infarction
- Cardiomyopathies (including hypertrophic cardiomyopathy and dilated cardiomyopathy)
Your CardioDNA™ report will also give you a thorough look at your food intolerances, nutrient metabolism, and physiological response to physical activity so you have a personalized lifestyle plan for reducing any existing risks.
*Note: CardioDNATM is available in all U.S. states except NY, PA, & RI.
Our DNA is the blueprint for our bodies and our health. And our unique genetic variations tell the story of who we are, as well as the lifestyle choices we should ideally make in order to activate the best versions of ourselves. Up until relatively recently, healthcare has predominately used a “one-size-fits-all" approach, which is simply not effective. None of us are the same, and healthcare should reflect that.
Cardiac DNA tests give us a more personalized healthcare option, allowing us to unlock our own valuable genetic information so we can make informed and empowered decisions, based on scientific data that’s unique to us. Especially if you have a family history of heart disease, or are concerned about your heart health, cardiac DNA tests are a safe, simple, and accessible tool for helping you choose the most appropriate route for current and future medical care based on your genetics.
In addition to this, CardioDNA™ tests also make sure that no matter your results, you have a wide range of additional genetic information to help you improve your health and properly manage your specific cardiac status.
1. Cardiac genetic testing for hereditary heart disease. (2022). Invitae.com. https://www.invitae.com/en/providers/cardiology/genetic-testing-insights
2. Musunuru, K., Hershberger, R. E., Day, S. M., Klinedinst, N. J., Landstrom, A. P., Parikh, V. N., Prakash, S., Semsarian, C., & Sturm, A. C. (2020). Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association. Circulation: Genomic and Precision Medicine, 13(4). https://doi.org/10.1161/hcg.0000000000000067
3. Genetic testing. (2022). Bhf.org.uk. https://www.bhf.org.uk/informationsupport/tests/genetic-testing#:~:text=Genetic%20testing%20can%20be%20used,of%20hair%2C%20skin%20or%20tissue.
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186468/
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC22154/
